April 23, 2015

Ackerson Lecture features University of Iowa researcher


Charles M. Brenner, Roy J. Carver chair of biochemistry and professor of internal medicine at Carver College of Medicine and the University of Iowa, will present “How Nicotinamide Riboside Promotes Weight Loss” from 4-5 p.m. April 29 in the Beadle Center, Room E103.

Brenner trained in molecular biology and genetics at Wesleyan University, Chiron Corporation and DNAX Research Institute before conducting his doctorate with Robert Fuller at Stanford University. He was the first to purify and characterize the Kex2 prohormone convertase and apply biochemical and genetic tools to characterize its substrate specificity and mechanism.

He was a Leukemia Society of America fellow with Gregory Petsko from 1993 to 1996 before taking an independent position at Thomas Jefferson University, where he earned funding from the National Institutes of Health and multiple private agencies. He was recruited to leadership positions at Dartmouth’s Norris Cotton Cancer Center in 2003 and to become Head of Biochemistry at the University of Iowa in 2009.

An expert in metabolism, he is best known for discovering nicotinamide riboside as a eukaryotic NAD precursor vitamin and for making novel contributions to our understanding of reversible modifications to DNA and proteins. He is also credited with re-invigorating the Department of Biochemistry and for launching the Obesity Research and Education Initiative at the University of Iowa.

For more information, contact Melanie Simpson at 402-472-9309 or msimpson2@unl.edu.